In particular, we identified two populations of transitional cells (C4: pre‐pro B cells and C5: pre‐activated B cells) according to their high expression of CD7, IL7R TNFAIP3 (for pre‐pro B cells) and BHLHE41, ZMAT3 (for pre‐activated B cells).[17] Interestingly, we observed that the proportion of activated B cells in lymph nodes with tumor metastasis are lower compared to lymph nodes without metastasis. Here, ZMAT3 is linked to neoplasm.