CXCR4 is expressed in a variety of tumor cells and considered to be associated with tumor stemness and metastasis.[7,8] Up‐regulated genes were significantly enriched in “CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL”, “DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX”, “INTEGRIN_CELL_SURFACE_INTERACTIONS” and “MET_PROMOTES_CELL_MOTILITY” pathways, which are related to the ability of tumor cells to penetrate the basement membrane and adhere to peripheral blood vessels to form micro‐metastases in distant places (Figure S4B,D, Supporting Information). Here, CXCR4 is linked to neoplasm.