CASZ1 and chromophobe renal cell carcinoma: Lastly, an analysis of the relationship between CASZ1 mRNA expression and overall survival (OS) from the TCGA database revealed that the CASZ1-low expression subgroup in ccRCC had a poor OS, compared to the CASZ1-high expression subgroup (P=0.05), but CASZ1 expression had no effect on OS in pRCC and chRCC (Fig. 1G).