FGF12 and psoriasis: For instance, topical application of a serine hydroxymethyltransferase inhibitor that suppresses keratinocyte proliferation in IMQ‐induced psoriasis models reduces expression of genes associated with psoriasis.[43] In addition, berberine, which inhibits cell division cycle 6 expression and proliferation of human keratinocytes by interfering with the JAK‐STAT3 signaling pathway, is a potential treatment option for psoriasis patients.[44] We observed significantly increased FGF12 expression in psoriatic lesions, particularly in the epidermis.