PRDX2 and colorectal cancer: The main result of this study was the finding that knockdown of PRDX2 inhibited the proliferation, growth, migration, invasion, and MMP9 activity of ES cells cultured in vitro and induced apoptosis, consistent with the reported procarcinogenic effects of PRDX2 in gastric, lung, and colorectal cancers [7, 8, 9].