By improving the expression of TJPs such as ZO-1 and Occludin, inhibiting pathological translocation of intestinal bacteria, and regulating the inflammatory cytokine environment within the liver, GA plays an important role in maintaining the balance of the gut-liver axis during the treatment of liver cirrhosis (Mohandas and Vairappan, 2020a,b). This evidence concerns the gene OCLN and cirrhosis of liver.