After QJ, the intestinal tissue structure of mice returned to normal, the expression levels of Claudin-1, Occludin and ZO-1 increased, the TJ apparatus damaged by CCl4 was restored, and liver inflammation and liver fibrosis were inhibited by repairing the intestinal epithelial barrier (Li et al., 2024). The gene discussed is OCLN; the disease is Hepatic fibrosis.