A nomogram (Figure 2) was developed to forecast ONFH likelihood in female SLE patients, using ten independent predictors that include disease duration at SLE onset, respiratory involvement, menstrual abnormalities, Sjögren's syndrome, osteoporosis, Anti-RNP, CYC, MMF, biologics, and the highest daily GC dose. The gene discussed is RNPC3; the disease is osteoporosis.