Among the 26 individual autoantigens of BC described to date (55–58), only 11 (MUC1 (CA 15.3), IMP2/p62, HSP60, Her2/Neu, Survivin, CDKN2A (p16), c-MYC, BRCA1, BRCA2, Cyclin B1, and NY-ESO-1 -which have been also described to be overexpressed in BC tissue samples-) out of them have been described as BC autoantigens in two or more studies, although their diagnostic ability (AUC, sensitivity, and specificity) was not calculated in all of them (Table 1) (58–61, 64–75). The gene discussed is BIRC5; the disease is breast cancer.