Secondly, we established comprehensive clinical information, such as gender, age, history of hepatitis B, maximum tumor diameter, number of intrahepatic tumors, tumor distribution differentiation, the situation of invasion and metastasis, ascites, WBC, HGB, PLT, ALB, TBIL, DBIL, ALT, GGT, AKP, PT, and AFP, and accurate follow-up data for the included patients. This evidence concerns the gene CYGB and hepatitis B virus infection.