Secondly, we established comprehensive clinical information, such as gender, age, history of hepatitis B, maximum tumor diameter, number of intrahepatic tumors, tumor distribution differentiation, the situation of invasion and metastasis, ascites, WBC, HGB, PLT, ALB, TBIL, DBIL, ALT, GGT, AKP, PT, and AFP, and accurate follow-up data for the included patients. The gene discussed is F2; the disease is neoplasm.