We and others have shown that in animal models of hypertension, expression of EGFR is elevated in kidneys (François et al., 2004; Benter et al., 2009a) including in the renal vasculature, such as the media of afferent and efferent renal arterioles (Swaminathan et al., 1996; Ying and Sanders, 2005). This evidence concerns the gene EGFR and Hypertension.