The Hemoglobin (Hb) (98.71 ± 23.68 VS 112.74 ± 23.31, P=0.001), CD3+ T cells (569.21 ± 436.72 VS 843.02 ± 596.09, P=0.005), and CD8+ T cells (428.36 ± 341.02 VS 616.06 ± 556.25, P=0.029) were significantly decreased in TB group compared with non-TB group. The gene discussed is GSTM1; the disease is tuberculosis.