This TF plays an essential role in regulating collagen fibrosis-related genes (COL3A1, COL4A1, TIMP1), immune-related gene (IL6), and cell-extracellular matrix interaction regulatory gene (THY1), which are all key pathways shared between IBD and SI-NET demonstrated by enrichment analysis. The gene discussed is ENSG00000280371; the disease is inflammatory bowel disease.