To further analyze the effect of IL2RG, EFNA3, and MTCP1 co‐expression on the survival time of ccRCC patients, we first carried out the establishment of a multigene prognostic model, according to the PI formula, PI (n) = β′1X′n1 + β′2X′n2 + β′3 X′n3, where the “β” value was the regression coefficient B value of the independent variable (mRNA) originated from the univariate Cox analysis of the three genes, and “X” denoted the expression of mRNA. This evidence concerns the gene MTCP1 and nonpapillary renal cell carcinoma.