Through morphology marker staining (insulin [INS]/pan cytokeratin [Pan-CK]/TOTO-3 [Thiazole Red Homodimer]), we observed no obvious change of islet areas, but a lower percentage of INS+ cells within islets of COVID-19 samples compared with control samples (Figures 1B and 1C), which is consistent with the previous reports.18 The gene discussed is INS; the disease is COVID-19.