CCL22 and neoplasm: In the present study, we were able to detect CCL22-expression by EC tumor cells as well as in the surrounding TME, and we found correlations for survival prognosis: High CCL22-expression in S/M areas close to EC is associated with poor OS, whereas the presence of CCL22+ M1-macrophages in distant myometrium and the CCL22-expression by tumor cells is linked to a better OS.