Conversely, within the severe OSA group, the serum renalase levels in individuals with hypertension displayed a significant decrease when contrasted with those in individuals without hypertension (2.94 ± 0.91 μg/ml vs 3.57 ± 1.05 μg/ml, p = 0.027). The gene discussed is RNLS; the disease is obstructive sleep apnea syndrome.