Additionally, a notable disparity was observed between the serum renalase levels in the non-OSA group without hypertension and the OSA group without hypertension, with the former displaying significantly lower levels (2.45 ± 0.32 μg/ml vs 3.57 ± 1.05 μg/ml, p < 0.0001). This evidence concerns the gene RNLS and obstructive sleep apnea syndrome.