With these, survival analysis revealed strong associations between the prognosis of NPC patients and the proportions of seven TLS-associated cell types, including B lineage cells (Naïve B, Memory B, GC B, and plasma cells), CD4_C8_CXCR5 and CD8_C8_CXCL13 T cells, and CXCL13+ CAFs, with higher cell proportions for better survival (Fig. 8a). The gene discussed is CXCR5; the disease is nasopharyngeal carcinoma.