CASP3 and neoplasm: Furthermore, spatial proximity analysis revealed that the number of apoptotic tumour cells (CASP3+PanCK+) interacting closely with plasma cells (IgG+; within 20 μm in distance) in the EBVhigh-TCA was significantly higher than that in the EBVlow-TCA (Fig. 3d, e and Supplementary Fig. 10a, b).