Knockdown of B4GALT1 by shRNA or siRNA (Supplementary Fig. S6C) in DLD1, HT29, and HCT116 CRC cells did not affect their adhesion (Supplementary Fig. S6D, E) but significantly attenuated their migration (Fig. 6D and Supplementary Fig. S6F) and invasion (Fig. 6E and Supplementary Fig. S6G); of note, cell viability was not affected (Supplementary Fig. S6H). Here, B4GALT1 is linked to colorectal carcinoma.