The ROSMAP/MAYO/MSBB XWAS identifies another set of SNPs associated with AD, however, the SH3BGRL gene is identified by both ROSMAP/MAYO/MSBB and KRONOS/Tgen and IL1RAPL1 is highlighted by both ROSMAP/MAYO/MSBB and BDR. The gene discussed is IL1RAPL1; the disease is Alzheimer disease.