TP53 and myelodysplastic syndrome: Multivariate analysis showed that age of ≥65 years(HR=2.47, 95% CI 1.43–4.26, P=0.001), mean corpuscular volume(MCV)of ≤100 fl(HR=2.62, 95% CI 1.54–4.47, P<0.001), and TP53 mutation(HR=2.31, 95% CI 1.29–4.12, P=0.005)were poor prognostic factors independent of the Revised International Prognostic Scoring System(IPSS-R)prognosis stratification in patients with MDS-E.