We then compared the overlap of autoreactive antigen enrichment (log2-fold change relative to healthy controls >1.5 in each group) between patients with AR RelB (n = 2), autoimmune polyglandular syndrome type 1 (APS-1, n = 14) and p52LOF/IκBδGOF variants (n = 12), as in a previous study (6). This evidence concerns the gene RELB and autoimmune polyendocrine syndrome type 1.