Variations which generate premature codon stop activating NMD have been linked to various diseases such as Duchenne muscular dystrophy (DMD) which affects myofibers where the absence of expression of the full-length dystrophin triggered major transcriptomic and functional abnormalities in myoblasts (García-Rodríguez et al. 2020). This evidence concerns the gene DMD and Duchenne muscular dystrophy.