Within 48 h the patient developed widespread exfoliativedermatitis, and all medication was stopped (CRP 154 mg/L, no eosinophilia,IgE 108 IU/mL, ALT 75 U/L max, viral serology negative apart fromCMV IgG) (Figure 1B–D).Multiple serial sections of a skin biopsy were evaluated, with resultssummarized in Table 1. This evidence concerns the gene CRP and Increased total eosinophil count.