Recently, AMHR2 expression in nongynecological cancers has been demonstrated in a large panel of tumor samples, showing that AMHR2 is expressed in the plasma membrane in more than 50% of the renal cell carcinomas, hepatocellular carcinomas, colorectal cancers, and NSCLC samples analyzed.13 Here, AMHR2 is linked to hereditary clear cell renal cell carcinoma.