Thus, chronic intermittent hypoxia (CIH) is one of the most common pathological features of OSA, which leads to multiple organ and systemic complications due to oxidative stress and systemic inflammation.[1] The liver, an important metabolic organ, is sensitive to hypoxic injury, which may be associated with chronic liver metabolic abnormalities and NAFLD caused by OSA.[5] In this study, we found that the liver function indices, ALT and AST, were positively correlated with OSA severity in patients with NAFLD. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.