Mice given MCD quickly develop steatosis and liver inflammation, followed by fibrosis within just 2-8 weeks of intervention.17 However, the mice experienced weight loss, reduced blood sugar levels, and increased insulin sensitivity, which contrasts with the human condition.18,19 Obesogenic diets, including various types of high-fat diets, are relatively more time-consuming in inducing NAFLD. Here, INS is linked to steatosis.