METTL3-mediated m6A modification in lnc-CTHCC is recognized by (IGF2BP1)/IGF2BP3, which maintains the stability of lnc-CTHCC and promotes HCC growth and metastasis through the lnc-CTHCC/hnRNPK/YAP1 axis (31). Here, IGF2BP1 is linked to hepatocellular carcinoma.