The percentages of IFN-γ+ of CD4+ and IFN-γ+ of CD8+ cell subsets in PBMC tended to be increased in SEA compared with HE (Figures 3H, I, p<0.1) but the relative expressions of IL-17 and IL-4 in the PBMC CD4+ and CD8+ T cell subsets were similar between the groups. The gene discussed is IL4; the disease is hereditary elliptocytosis.