According to the TRN analysis, SOX4 can be regulated by HOXC6, whereas DLX5 can be regulated by SOX4, FOXM1, and ETV4 (Figure 3), and according to the co-regulatory network analysis, they both participate in the formation of TF complexes in both subtypes of lung cancer (NSCLC and SCLC) (Supplementary Table 1). Here, HOXC6 is linked to small cell lung carcinoma.