According to the TRN analysis, SOX4 can be regulated by HOXC6, whereas DLX5 can be regulated by SOX4, FOXM1, and ETV4 (Figure 3), and according to the co-regulatory network analysis, they both participate in the formation of TF complexes in both subtypes of lung cancer (NSCLC and SCLC) (Supplementary Table 1). The gene discussed is DLX5; the disease is lung cancer.