TNPO1 and cancer: Our global transcriptomic analysis suggests a complex crosstalk between the microbiome and cancer TRN, as shown by the co-expression of common DEGs that codify for membrane receptors and TFs, and consequently, the possible participation in the same biological process, along with all experimental studies that have demonstrated that the interaction of the microbiome and specific receptors identified as common DEGs in cancer might be able to activate signaling pathways that regulate gene expression.