JUN is overregulated in three of the five datasets and is related to: 1) colon cancer signaling pathways along with MYC; 2) the focal adhesion pathway along with ELK1; 3) pathways in cancer along with ELK1 and MYC; 4) EBV infection along with MYC; and 5) angiogenesis. The gene discussed is MYC; the disease is colonic neoplasm.