The observed decrease was associated with an elevation in PINK1, Parkin, and DJ1 (protein deglycase), indicating that Akap1 and BMI1 could be promising targets for therapeutic intervention in the treatment of ALI/ARDS (Narala et al., 2018; Hernández-Cuervo et al., 2022; Soundararajan et al., 2022). This evidence concerns the gene AKAP1 and acute respiratory distress syndrome.