In comparison to PNAR patientswithout PH, the PH group exhibited higher rates of renal dysfunction (10.4% vs.0.0%, p = 0.014), increased Society of Thoracic Surgeons scores (6.4 ± 1.9 vs. 4.7 ± 1.6, p < 0.001), and elevated Nterminal fragment of pro–brain natriuretic peptide (NT-proBNP).Transthoracic ultrasound examination revealed that patients with PH displayedlower left ventricular ejection fraction, larger left ventricle dimension, andmore frequent moderate to severe tcuspid regurgitation (TR). The gene discussed is NPPB; the disease is Abnormal renal physiology.