Other reports on CNS tumors with EWSR1-PLAGL1 rearrangement [10, 12, 13, 16, 20, 21] have included a frontal lobe glioneuronal tumor with a ganglion cell component [10], a tumor identified by retrospective methylation profiling of anaplastic gangliogliomas [13, 15], and a case diagnosed as an INI1-deficient atypical teratoid/rhabdoid tumor [12]. The gene discussed is SMARCB1; the disease is neoplasm.