OLFM4 and hepatocellular carcinoma: In an article published in 2023, Feng et al. reported the significant enrichment of three proteins, olfactomedin 4 (OLFM4), growth differentiation factor 15 (GDF15), and hepatocellular carcinoma-derived growth factor (HDGF), in uEVs from patients with HCC using an array-based amphiphilic supramolecular probe (ADSP)-modified NC membrane platform [120].