EPCAM and hepatocellular carcinoma: Through fluorescence-activated cell scanning (FACS), AnnexinV+ EpCAM+ ASGPR1+ EVs are identified as potential biomarkers to distinguish between HCC patients and cirrhotic patients without detectable tumors, with an area under the curve (AUC) of 0.732 and exhibit a notable decrease by the seventh day following surgery [104].