The expression of HDAC4, CTCF and Nup50 was unchanged while that of TP63 was found lower in AD-iPSC compared with control cells (WB optical density: C-iPSC 1 ± 0.04, AD-iPSC 0.42 ± 0.06, P < 0.01 t-test, n = 3; Suppl. The gene discussed is NUP50; the disease is Alzheimer disease.