RBFOX3 and Alzheimer disease: We found that the number of BrdU+/NeuN+ cells was lower in AD-GFP mice compared with WT-GFP mice but was increased in AD-Nup153-GFP mice (BrdU+/NeuN+: WT-GFP 635 ± 33, AD-GFP 234 ± 41, AD-Nup153-GFP 494 ± 46 P < 0.05 ANOVA followed by Bonferroni test, n = 4 WT, n = 5 AD, n = 7 AD-Nup153; Fig. 4B).