In contrast, some identified mRNAs significantly upregulated in miR-141 transduced cells, such as NEB encoding for nebulin protein, ASGR1 encoding for asialoglycoprotein receptor 1, and CPE encoding for carboxypeptidase E. Most of them play a potential role in tumorigenesis and cancer diagnosis, particularly in hepatic patients [43, 44]. This evidence concerns the gene CPE and cancer.