Alternatively, the most increased mRNAs were linked with the cancer progression and development, such as NEB encoding for nebulin protein, ASGR1 encoding for asialoglycoprotein receptor 1, and CPE encoding for carboxypeptidase E (Fig. 2C). To check the direct interaction between miR-141 and identified genes by microarray analysis, the in-silico miRWalk tool was used to detect the possible binding site of miR-141 and targeted sequences. Here, CPE is linked to cancer.