Indeed, certain AS-lncRNAs have been shown to play roles in AD pathology, including BACE1-AS, SORL1-AS(51A), LRP1-AS, MAPT-AS1, BDNF-AS, MAGI2-AS3, EBF3-AS, NAT-RAd18D, and SOX21-AS1. This evidence concerns the gene SORL1 and Alzheimer disease.