MAPT and Alzheimer disease: Several tools, such as computed tomography (CT), positron emission tomography (PET), structural magnetic resonance imaging (sMRI), resting-state functional magnetic resonance imaging (Rs-fMRI), and cerebrospinal fluid analysis of β-amyloid (Aβ) or tau protein (total tau [T-tau] and phosphorylated tau [P-tau]) concentrations have been suggested as potential diagnostic methods for AD.