Among somatostatin receptors, [68Ga]Ga-DOTA-TATE has the highest affinity for somatostatin receptors type 2 [18], widely expressed specifically by pro-inflammatory M1 macrophages [17], and for this reason, has already been used successfully to detect macrophagic activation in atherosclerosis-related inflammatory processes [49–51]. The gene discussed is SSTR2; the disease is atherosclerosis.