The incidence rate of relapse in the global sample was 6.8 per 1,000 patients-month (95% CI, 4.3–10.7), increasing to 38.2 per 1,000 patients-month (95% CI, 17.2–85) in patients with positive LNs and H-AF levels and to 22.5 per 1,000 patients-month (95% CI, 10.1–50) in patients with positive LNs and H-EpCAM levels. Here, EPCAM is linked to atrial fibrillation.