The elevated expression of ZNF8 was significantly associated with a higher histological grade, lymph node metastasis, HER‐2 receptor positivity while no significant correlation was observed with tumor size, and molecular types of breast cancer both in our Cohort 1 and The Cancer Genome Atlas Program (TCGA) samples (Figure 2B,C; Table S1 and Figure S1, Supporting Information). This evidence concerns the gene ZNF8 and neoplasm.