BMI1 and cardiac hypertrophy: Our recent study also reported that adeno‐associated viral vector (AAV) serotype 9‐CMV‐Bmi‐1‐RING1B could promote the ubiquitination of GATA4 and prevent GATA4‐dependent senescence‐associated pathological cardiac hypertrophy.[19] A previous study showed that eight serotypes of AAV, including 1, 4, 5, 6, 7, 9, rh10, and rh39, were successfully infected into osteoblasts in vitro.