To investigate this, we compared glycolytic parameters among tumor cells and CD8+ T cells, CD4+Foxp3– cells (effector T cells [Teffs]), and CD4+Foxp3+ cells (Tregs) within the TME from established B16-YFP tumors excised from mice treated with LDHi for 10 days (Figure 4A). This evidence concerns the gene FOXP3 and neoplasm.