NONO and neoplasm: In contrast, among the 91 genes upregulated in metastatic cells from highly metastatic tumor models, many genes were indicative of high stress-response signaling, including several heat shock proteins (HSPB1, HSPA8, HSPA6, HSPH1, HSP90AB3P, DnaJs A1, B1, C3, and BAG3), PPM1G, and genes involved in DNA damage repair (SSRP1, NONO).