SOD1 and amyotrophic lateral sclerosis: The expression of RABGGTB was significantly high in peripheral monocyte and monocyte-derived macrophages from patients with ALS, but the data collected come from sporadic ALS, and these data are not representative of familial ALS (fALS), such as those with mutations in the Cu/Zn-superoxide dismutase (SOD1) gene, so we detect the expression of RABGGTB in monocytes of SOD1G93A mice and found that the expression of RABGGTB was significantly upregulated in monocytes of SOD1G93A mice.