DUOX2 and alkaline phosphatase measurement: In this study, we first collected blood samples from AP patients and healthy people, established AP cell model with human pancreatic duct cells (H6C7) stimulated by caerulein, observed the apoptosis and growth of cells, as well as the expression of RNA and protein, and detected the release level of inflammatory factors and the interaction between DUOX2 and miR-605-3p.