Additionally, CFTR mutations affect phagocytosis process (Jaganathan et al., 2022), further decreasing bacterial clearance in the airways and opening up the possibility for colonization by opportunistic pathogens, such as Mycobacterium abscessus (Mab), which is the most common nontuberculous mycobacterial lung disease etiological agent in CF patients, representing a major cause of morbidity and mortality. The gene discussed is CFTR; the disease is cystic fibrosis.