In terms of the CD4 lymphopenia, the patient had a low CD4 count of 82 cells/μL in June 2020, 9 months after CAR T-cell therapy and before disease relapse, however following initiation of CD20/CD3 BsAb, CD4 T-cell count dropped to a nadir of 5 cells/μL (Supplementary Figure 1). The gene discussed is CD4; the disease is lymphopenia.