To further explore the normalization of relevant psoriasis gene sets with treatment, we employed gene set variation analysis using the meta-analysis derived-3 psoriasis transcriptome gene sets and curated genes sets for Th17 cells, IL-17-stimulated keratinocytes, and regulatory T cell responses (Krueger et al, 2019; Tian et al, 2012). The gene discussed is IL17A; the disease is psoriasis.