Meanwhile, PRKAR1A and SDCBP may serve as novel biomarkers for early diagnosis,80 and the monocyte-associated biomarkers CUX1, CTSD, and ADD3 can be used for early prediction of post-acute myocardial infarction development of heart failure and potential therapeutic targets after heart failure caused by acute myocardial infarction.81 This evidence concerns the gene PRKAR1A and heart failure.