EYS and retinitis pigmentosa: Eyes shut interacts with matriglycan O-mannosyl glycans on α-DG to stabilise the photoreceptor ribbon synapse in phototransductive interactions with retinal bipolar neurons (Husain et al. 2006; Liu et al. 2020), maintain photoreceptor morphology and visual acuity. Mutations in Eys result in vision impairment in retinitis pigmentosa (Suvannaboon et al. 2022).