PITX1 and disorder of sexual differentiation: Additionally, 21.88% of XX DSD pigs showed copy number increase or decrease on the SV of chromosome 3 (231801–479100 bp), covering the genes PDGFA, PRKAR1B, and DNAAF5. Interestingly, in contrast to the WGS results, 31.25% of XX DSD pigs showed an increase in the copy number of the pituitary homeobox paired homeodomain transcription factor 1 gene (PITX1).